Have you ever felt despair?

So I’m feeling a little down. Well, a lot down. Something uplifting for me is reading. So, I’m reading the Dresden Files. Jim Butcher’s first book in the series is Storm Front. I open to chapter 18 and read:

Have you ever felt despair? Absolute hopelessness? Have you ever stood in the darkness and known, deep in your heart, in your spirit, that it was never, ever going to get better?…

[Source, Storm Front (Dresden Files), Chapter 18]